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Event ID : ADDF_SF
Alzheimers Drug Discovery Foundation
Alzheimers Drug Discovery Foundation
February 10-12, 2013


The Drug Discovery for Neurodegeneration conference advances drug discovery for neurodegenerative diseases by educating scientists on the process of translating basic research into novel therapies.

The course is designed to give participants knowledge and relevant resources about this field of scientific investigation and address the associated barriers and challenges.

The program will focus on Alzheimerís disease, Parkinsonís disease, Amyotrophic Lateral Sclerosis and Multiple Sclerosis.

COURSE OBJECTIVES

1.

Train a cadre of interdisciplinary scientists in the principles of drug discovery for neurodegenerative disease

2.

Provide a platform to exchange ideas, knowledge and resources about drug discovery for neurodegenerative disease

3.

Stimulate pre-clinical research in the discovery and testing of novel compounds aimed at the prevention and treatment of neurodegenerative disease

4.

Build public-private partnerships that will accelerate drug discovery for neurodegenerative disease.

Table of Contents
7th ANNUAL DRUG DISCOVERY FOR NEURODEGENERATION CONFERENCE
I. Basics of Medicinal Chemistry
II. Drug Discovery: From Screening to Clinical Candidate
III. Strategies for Challenging CNS Targets
IV. Commercialization Strategies: Developing Science into Products


February 10th, 2013
7th ANNUAL DRUG DISCOVERY FOR NEURODEGENERATION CONFERENCE
______________________

Welcome and Opening Remarks Challenges and Opportunities in Academic Drug Discovery

Speaker(s) : Howard Fillit, MD



______________________

Preclinical Therapeutics Development for Neurological Disorders: Funding and Resources

Speaker(s) : Lorenzo M. Refolo, PhD , Rajesh Ranganathan, PhD





February 11th, 2013
I. Basics of Medicinal Chemistry
______________________

Overview: Medicinal Chemistry Rules of Thumb, Myths and Realities in CNS Drug Discovery

Speaker(s) : D. Martin Watterson, PhD



______________________

Synthetic Chemistry Essentials for Biologists

Speaker(s) : Jeff C. Pelletier, PhD



______________________

Natural Products as Drug Starting Points

Speaker(s) : Frank E. Koehn, PhD





February 11th, 2013
II. Drug Discovery: From Screening to Clinical Candidate
______________________

Improving Clinical Success Through Optimal Target Validation

Speaker(s) : Kalpana M. Merchant, PhD



______________________

New Trends in High Throughput Screening (HTS)

Speaker(s) : Michelle Arkin, PhD



______________________

Compound Optimization after HTS: From Hit to Lead

Speaker(s) : Kurt R. Brunden, PhD



______________________

Absorption, Distribution, Metabolism, Excretion and Toxicology (ADME-Tox) in Compound Refinement

Speaker(s) : Katya Tsaioun, PhD



______________________

Designing a Therapeutic Animal Study

Speaker(s) : Kelly Bales, PhD



______________________

Requirements for an IND and Early Considerations

Speaker(s) : Edward G. Spack, PhD



______________________

An Academic Perspective on Drug Discovery Services: Center and CROs

Speaker(s) : Marcie Glicksman, PhD



______________________

ADDF ACCESS Program and Closing Remarks

Speaker(s) : Rachel Lane, PhD





February 12th, 2013
III. Strategies for Challenging CNS Targets
______________________

Plenary: Systematic Drug Repositioning for Neurodegenerative and Other Diseases

Speaker(s) : Pankaj Agarwal, PhD



______________________

Challenges of Protein-Protein/Protein-Peptide Targets

Speaker(s) : Jim Wells, PhD



______________________

Utility of Stem Cells for Preclinical Drug Discovery

Speaker(s) : Adam Rosenthal, PhD



______________________

Peptide Therapeutics and Mechanisms for Intranasal Delivery

Speaker(s) : Bruce Morimoto, PhD



______________________

Developing Therapeutic Antibodies for Neurodegenerative Disease

Speaker(s) : Ryan Watts, PhD





February 12th, 2013
IV. Commercialization Strategies: Developing Science into Products
______________________

Creative Pharma-Academia Partnership Models for Accelerating Drug Discovery

Speaker(s) : Teri Melese, PhD



______________________

Landscape of Funding Opportunities for Biotechnology Companies

Speaker(s) : Melinda Richter, MBA



______________________

Starting Your Own Biotech: Challenges and Pitfalls

Speaker(s) : Frank M. Longo, MD, PhD



______________________

How Foundations Can Bridge the Funding and Resources Gap

Speaker(s) : Kuldip Dave, PhD



______________________

Partnerships and Collaboration:†Translating Early Space Innovation into Therapeutics

Speaker(s) : Steven Bartz, PhD




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